Curious for those of you running a GLP with cagrilintide, at what point did you add the cagrilintide?
I’ve been on GLP3 for probably 10 months now, currently at 9mg a week with a bit of room left to titrate doses up.
Ive got about 5 weeks left in a maintenance health phase and then am planning a 10 week cut. Hunger is pretty bad right now, I’ve been going back and forth between titrating up or adding Cag but I want to make sure I have room for the cut. I think a break is going to have to happen after the cut to bring overall required GLP dose back down though.
Anyone have experience from a similar situation?
I'm curious to this too tbh. I have only tried GLP3, but i was wondering how the switch to say GLP2 would be? would it let me still feel the effects of the reduced hunger while it lets me reset on the GLP3. I as well take HGH and that alone fat lipolysis might hold my stats or goals, I think possibly to many people might be worried about the cravings vs the actual results. I figure as long as I can still eat healthy while having little rebound it might still support my goals.
anyone have thought to this?
@niktok wrote:
I'm curious to this too tbh. I have only tried GLP3, but i was wondering how the switch to say GLP2 would be? would it let me still feel the effects of the reduced hunger while it lets me reset on the...
My understanding is, you are still hitting the two shared receptors so you won’t be resetting, just losing glucagon activation.
Need to actually stop all GLPs for receptors to re-sensitize
@wooddhaven Sorry this reply was meant for another post you had said about showing the last time replied vs the created date. I commented on the wrote post with the intention to address the other comment you had stated.
@survivalism wrote:
My understanding is, you are still hitting the two shared receptors so you won’t be resetting, just losing glucagon activation.Need to actually stop all GLPs for receptors to re-sensitize
Appreciate the clarification. That makes sense on the shared receptor point if you’re talking about switching from a triple agonist to a dual agonist.
My only hesitation is that cagrilintide seems to be a different mechanism rather than just more GLP/glucagon activity, so I’m not sure it fits the same “no reset” logic.
I also haven’t seen strong human data showing you need to fully stop all GLP-based meds for some broad receptor re-sensitization effect. It seems more established that certain effects can diminish over time, which feels a little different from saying a full reset is required.
@wooddhaven wrote:
As someone who just switched to Reta I think from what I've heard or read Cag can be a great addition to your Reta if you don't think your getting the hunger suppression you need. If that happens to me I think I'd give it a shot. No pun intended...lol.
We actually plan to restructure the forum slightly as we progress
@VialTalk wrote:
@wooddhaven wrote:
As someone who just switched to Reta I think from what I've heard or read Cag can be a great addition to your Reta if you don't think your getting the hunger suppression you need. If that happens to me I think I'd give it a shot. No pun intend...
Not sure I understand this reply.
@VialTalk wrote:
@wooddhaven Sorry this reply was meant for another post you had said about showing the last time replied vs the created date. I commented on the wrote post with the intention to address the other comment you...
I kinda figured. Just wanted to make sure unless I had missed something. Thanks.
