I chose HGH over tesamorelin while cutting with retatrutide because I wanted something more direct and consistent, especially with my schedule.
I wake up for work at 3:15 AM, and before I leave, I take my HGH shot along with my GHK-Cu shot. After that, I don’t eat until around 8:00 AM. During that window, it’s just coffee and electrolytes. That routine works well for me and fits cleanly into my mornings.
Part of why I chose HGH is that it feels more straightforward. Tesamorelin relies on stimulating your body to release more of its own growth hormone, while HGH is direct. For my goals during a cut, I preferred that approach. Since I’m already using retatrutide to help with appetite control and staying in a deficit, I wanted something alongside it that I felt was better suited for muscle retention, recovery, and overall body composition.
With my early mornings, fasted period, and the way I structure things before work, HGH just made more sense to me. I like knowing exactly what I’m taking and keeping the setup simple. Tesamorelin may be a good option for some people, but for what I’m doing right now, HGH seemed like the better fit.
Retatrutide is already doing a lot of the heavy lifting on the cutting side, so my goal was to pair it with something that supports holding onto muscle and improving how I look while leaning out. That’s really why I went this route.
Interested to hear from anyone who has run HGH vs tesamorelin during a cut, especially while also using retatrutide
A few key reasons i chose HGH over a GHRP:
@survivalism wrote:
A few key reasons i chose HGH over a GHRP:
1. I dont have to worry about being in a fasted state
2. I can push my igf1 and zscore higher than what is possible with a GHRP
3. HGH is predictable, GHRP is not
one thing to note.
igf1 serum testing is a completely arbitrary and worthless biomarker, it's not an indicator of protocol efficacy.
the igf1 blood test only tests igf1 in serum, and is unable to differentiate between bound and freely available igf1.
Almost all igf1 in serum is bound to one of several igf1 binding proteins (igfbp)
the most common of which is igfbp1 which renders the igf1 inert and unusable.
so higher serum igf1 does not necessarily (or even likely) indicate higher igf1 in tissue
it's just as likely that the elevated igf1 scores seem on bloodwork are a result of more igf1 being bound to igfbp1, preventing it from entering muscle tissue and remaining in serum doing nothing
GH is simply, and objectively, superior to any and all secretagogues by every metric, including cost efficacy.
For males it should always be chosen before the growth hormone secreting/stimulating peptides unless the legal and/or supply concerns prevent it as a viable option.